SLU-PP-332: what the research shows
Not a peptide: a lab compound that makes mice’s muscles behave as if they had exercised.
Also known as Often called an “exercise pill”

At a glance
Not approved. Studied only in mice.
This compound is not a peptide, but is often discussed alongside them.
What is SLU-PP-332?
SLU-PP-332 is a small chemical, not a peptide. It switches on ERR receptors, which help control how muscles burn energy.
How does SLU-PP-332 work?
In mice it turns on part of the body’s natural response to aerobic exercise, without the exercise.
What does the research show?
- In obese mice, it mimicked effects of exercise and reduced fat mass (2024 study).
- It has not been tested in people.
Known risks and side effects
- Its effects and safety in people are completely unknown.
Is SLU-PP-332 approved?
Mostly studied in cells and animals, with little or no proper testing in people.
Not approved. Studied only in mice.
From the community
Watch: SLU-PP-332 and related science
We have not selected a reliable dedicated SLU-PP-332 video. These lessons cover the relevant biology and research methods; the compound-specific evidence is in the sources below.
Khan Academy
Mitochondria: structure and cellular energy
A foundation for reading mitochondrial research. It does not demonstrate a benefit from any experimental compound.
Biology education
Related biology
Background on mitochondria and cellular energy for understanding SLU-PP-332. It does not demonstrate benefits of this compound or formulation.
Progress, Potential, and Possibilities
NAD coenzymes, metabolic stress and new interventions
A leading NAD scientist on what the molecule does and what boosting it might achieve.
Interview with Charles Brenner, PhD, NAD researcher at City of Hope
Related biology
Background on NAD metabolism for understanding SLU-PP-332. It does not demonstrate benefits of this compound or formulation.
Sources and references
- A Synthetic ERR Agonist Alleviates Metabolic SyndromeBillon et al. · Journal of Pharmacology and Experimental Therapeutics · 2024
VETUD Learn explains published research in plain language. It is general information, not medical advice. Talk to a doctor before starting, stopping or changing any treatment.
In the research shop
Check the catalog for related laboratory research materials. These products are separate from the approved medicines and clinical trial formulations discussed here.
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